The transcription factor, Lmx1b, is necessary for the development of the principal trigeminal nucleus-based lemniscal pathway

Little is known of transcriptional mechanisms underlying the development of the trigeminal (V) principal sensory nucleus (PrV), the brainstem nucleus responsible for the development of the whisker-to-barrel cortex pathway. Lmx1b, a LIM homeodomain transcription factor, is expressed in embryonic PrV....

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Veröffentlicht in:	Molecular and cellular neuroscience 2010-08, Vol.44 (4), p.394-403
Hauptverfasser:	Xiang, Chuanxi, Zhang, Kai-Hua, Yin, Jun, Arends, Joop J.A., Erzurumlu, Reha S., Jacquin, Mark F., Chen, Zhou-Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Afferent Pathways - physiology Animals Animals, Newborn Barrels Bax protein bcl-2-Associated X Protein - deficiency Body Patterning - genetics Cell Death - genetics Drg11 Homeodomain Proteins - genetics Homeodomain Proteins - physiology LIM-Homeodomain Proteins Lmx1b Mice Mice, Inbred C57BL Mice, Knockout Nerve Tissue Proteins - deficiency Nerve Tissue Proteins - genetics Pattern formation Thalamus - cytology Thalamus - embryology Transcription factor Transcription Factors - deficiency Transcription Factors - genetics Transcription Factors - physiology Trigeminal Ganglion - cytology Trigeminal Ganglion - embryology Trigeminal Nuclei - cytology Trigeminal Nuclei - embryology Trigeminal Nuclei - metabolism Vibrissae - innervation Whiskers
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