Lymphangiogenesis-independent resolution of experimental edema

Vascular endothelial growth factor (VEGF)-C is necessary for lymphangiogenesis, and excess VEGF-C has been shown to be ameliorative for edema produced by lymphatic obstruction in experimental models. However, it has recently been shown that edema can resolve in the mouse tail even in the complete ab...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2010-07, Vol.299 (1), p.H46-H54
Hauptverfasser:	Ongstad, Emily L, Bouta, Echoe M, Roberts, Jaclynn E, Uzarski, Joseph S, Gibbs, Sara E, Sabel, Michael S, Cimmino, Vincent M, Roberts, Melissa A, Goldman, Jeremy
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - administration & dosage Blood vessels Capillaries - metabolism Capillaries - physiopathology Cardiovascular disease Disease Models, Animal Female Lymph - metabolism Lymphangiogenesis Lymphedema - metabolism Lymphedema - physiopathology Lymphography Macrophages - metabolism Mice Mice, Inbred BALB C Mice, Inbred C57BL Neovascularization, Physiologic Rodents Signal Transduction Skin Time Factors Tissues Vascular Endothelial Growth Factor C - metabolism Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors Vascular Endothelial Growth Factor Receptor-2 - metabolism Vascular Endothelial Growth Factor Receptor-3 - antagonists & inhibitors Vascular Endothelial Growth Factor Receptor-3 - metabolism Wound Healing
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