Mass Spectrometric Identification of Oxidative Modifications of Tryptophan Residues in Proteins: Chemical Artifact or Post-Translational Modification?

Oxidative modification of tryptophan to kynurenine (KYN) and N-formyl kynurenine (NFK) has been described in mitochondrial proteins associated with redox metabolism, and in human cataract lenses. To a large extent, however, previously reported identifications of these modifications were performed us...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Society for Mass Spectrometry 2010-07, Vol.21 (7), p.1114-1117
Hauptverfasser:	Perdivara, Irina, Deterding, Leesa J., Przybylski, Michael, Tomer, Kenneth B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical Chemistry Analytical, structural and metabolic biochemistry Animals Antibodies Antibodies, Monoclonal - chemistry Antibodies, Monoclonal - metabolism Application Note Bioinformatics Biological and medical sciences Biotechnology Chains Chemistry Chemistry and Materials Science Chromatography, Liquid Digestion Dithiothreitol - chemistry Electrophoresis Electrophoresis, Polyacrylamide Gel Fingerprinting Fundamental and applied biological sciences. Psychology General aspects, investigation methods Humans Kynurenine - chemistry Kynurenine - metabolism Liquid chromatography Mass spectrometry Metabolism Mice Molecular Sequence Data Organic Chemistry Oxidation Oxidation-Reduction Peptide Mapping - methods Protein Processing, Post-Translational Proteins Proteomics Proteomics - methods Residues Separation Tandem Mass Spectrometry - methods Trypsin - metabolism Tryptophan Tryptophan - chemistry Tryptophan - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!