Chocolate Matrix Factors Modulate the Pharmacokinetic Behavior of Cocoa Flavan-3-ol Phase II Metabolites Following Oral Consumption by Sprague−Dawley Rats

The impact of carbohydrates and milk on the bioavailability of catechin (C) and epicatechin (EC) from chocolate has been previously studied. However, little data exist regarding potential modulation of the phase II metabolism by these chocolate matrix factors. The objectives of this study were to as...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2010-06, Vol.58 (11), p.6685-6691
Hauptverfasser:	Neilson, Andrew P, Sapper, Teryn N, Janle, Elsa M, Rudolph, Ralf, Matusheski, Nathan V, Ferruzzi, Mario G
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Bioactive Constituents Biological and medical sciences Cocos - chemistry Confectionery products and chocolate industries, honey Feeding. Feeding behavior Flavonoids - administration & dosage Flavonoids - metabolism Flavonoids - pharmacokinetics Food industries Fundamental and applied biological sciences. Psychology Male Plant Extracts - administration & dosage Plant Extracts - metabolism Plant Extracts - pharmacokinetics Rats Rats, Sprague-Dawley Vertebrates: anatomy and physiology, studies on body, several organs or systems
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