Omental immune aggregates and tumor metastasis within the peritoneal cavity

The omentum, an important peritoneal tissue, is studded with a high number of immune aggregates, or “milky spots,” the number, function, and phenotype of which is largely unknown. We have analyzed the immune composition on the normal omentum and also have shown that both free immune cells and tumor...

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Veröffentlicht in:	Immunologic research 2009-12, Vol.45 (2-3), p.185-194
Hauptverfasser:	Sorensen, Elizabeth W., Gerber, Scott A., Sedlacek, Abigail L., Rybalko, Viktoriya Y., Chan, Winnie M., Lord, Edith M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergology Animals Biomedical and Life Sciences Biomedicine Cell growth Cell Line, Tumor Female Flow Cytometry Humans Immune system Immunology Immunophenotyping Internal Medicine Lymphocyte Subsets - immunology Lymphocyte Subsets - metabolism Medicine/Public Health Metastasis Mice Mice, Inbred C57BL Microscopy, Fluorescence Neoplasms, Experimental - immunology Neoplasms, Experimental - metabolism Neoplasms, Experimental - pathology Omentum - blood supply Omentum - immunology Omentum - metabolism Ovarian cancer Ovarian Neoplasms - immunology Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Peritoneal Cavity - pathology Peritoneal Neoplasms - immunology Peritoneal Neoplasms - metabolism Peritoneal Neoplasms - secondary RNA, Messenger - genetics RNA, Messenger - metabolism Tissues Transplantation, Heterologous Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor C - genetics Vascular Endothelial Growth Factor C - metabolism Vascular Endothelial Growth Factor Receptor-3 - metabolism
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