A Francisella novicida pdpA mutant exhibits limited intracellular replication and remains associated with the lysosomal marker LAMP-1

1 Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada 2 Department of Biology, University of Victoria, Victoria, BC, Canada Several genes contained in the Francisella pathogenicity island (FPI) encode proteins needed for intracellular growth and virulence of Fra...

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Veröffentlicht in:	Microbiology (Society for General Microbiology) 2009-05, Vol.155 (5), p.1498-1504
Hauptverfasser:	Schmerk, Crystal L, Duplantis, Barry N, Howard, Perry L, Nano, Francis E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology Biological and medical sciences Cell Line Cells, Cultured DNA Replication Female Francisella - genetics Francisella - metabolism Francisella - pathogenicity Francisella novicida Francisella tularensis Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Bacterial Gram-Negative Bacterial Infections - genetics Gram-Negative Bacterial Infections - metabolism Gram-Negative Bacterial Infections - microbiology Humans Lysosomal-Associated Membrane Protein 1 - genetics Lysosomal-Associated Membrane Protein 1 - metabolism Lysosomes - genetics Lysosomes - metabolism Mice Mice, Inbred BALB C Microbial Pathogenicity Microbiology Miscellaneous Protein Binding Sequence Deletion Virulence Virulence Factors - genetics Virulence Factors - metabolism
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