Zebrafish fetal alcohol syndrome model: effects of ethanol are rescued by retinoic acid supplement

Abstract This study was designed to develop a zebrafish experimental model to examine defects in retinoic acid (RA) signaling caused by embryonic ethanol exposure. RA deficiency may be a causative factor leading to a spectrum of birth defects classified as fetal alcohol spectrum disorder (FASD). Exp...

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Veröffentlicht in:	Alcohol (Fayetteville, N.Y.) N.Y.), 2010-11, Vol.44 (7), p.707-715
Hauptverfasser:	Marrs, James A, Clendenon, Sherry G, Ratcliffe, Don R, Fielding, Stephen M, Liu, Qin, Bosron, William F
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced - prevention & control Acids Animals Biosynthesis Cell adhesion & migration Disease Models, Animal Embryo, Nonmammalian Embryogenesis Embryonic Development - drug effects Embryos Ethanol Ethanol - administration & dosage Ethanol - toxicity Evacuations & rescues Experiments Female Fetal Alcohol Spectrum Disorders - prevention & control Fetal alcohol syndrome Gastrulation Psychiatry Retinoic acid Software Somitogenesis Tretinoin - administration & dosage Zebrafish Zebrafish - embryology
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