Long-term reproducibility of ambulatory blood pressure is superior to office blood pressure in the very elderly
Although it is known that reproducibility of ambulatory blood pressure (BP) is superior to office BP in middle-aged subjects, little is known in older age groups. Hence, we compared the long-term reproducibility of ambulatory and office BP readings in subjects over the age of 75 years. A cohort of 7...
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| Veröffentlicht in: | Journal of human hypertension 2010-11, Vol.24 (11), p.749-754 |
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| creator | Campbell, P Ghuman, N Wakefield, D Wolfson, L White, W B |
| description | Although it is known that reproducibility of ambulatory blood pressure (BP) is superior to office BP in middle-aged subjects, little is known in older age groups. Hence, we compared the long-term reproducibility of ambulatory and office BP readings in subjects over the age of 75 years. A cohort of 72 subjects 75–90 years of age (mean, 82 years at baseline) had repeat office and ambulatory BPs 2 years apart under similar conditions. On the same day, patients underwent office BP measurements by a semi-automated device and then by ambulatory BP monitoring. Awake and sleep periods were divided according to a diary kept by each patient. The agreement between studies was assessed using the standard deviation of the differences (SDD) and Bland–Altman plots. There were minimal mean changes in office, 24-h, and awake and sleep mean BP values between baseline and 2 years later. The SDDs between visits were lower for 24-h BP compared with the office BP (11.7/5.9 mm Hg versus 17.8/9.0 mm Hg,
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| doi_str_mv | 10.1038/jhh.2010.8 |
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P
<0.01). The SDD for 24-h BP was also lower than the SDDs for the awake and sleep BP (
P
<0.05). Nocturnal BPs defined by absolute values were more reproducible than categories of dippers and non-dippers. These data demonstrate that long-term reproducibility of 24-h BP is superior to office measurements for very elderly subjects. In a clinical trial involving this age group, far fewer subjects would be required if 24-h BP was the primary efficacy endpoint rather than the office BP.</description><identifier>ISSN: 0950-9240</identifier><identifier>EISSN: 1476-5527</identifier><identifier>DOI: 10.1038/jhh.2010.8</identifier><identifier>PMID: 20200549</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/699/75/243 ; 692/700/139/1735 ; 692/700/1518 ; Age Factors ; Aged ; Aged, 80 and over ; Arterial hypertension. Arterial hypotension ; Biological and medical sciences ; Blood and lymphatic vessels ; Blood Pressure ; Blood Pressure Determination - methods ; Blood Pressure Monitoring, Ambulatory ; Brain - pathology ; Cardiology. Vascular system ; Circadian Rhythm ; Clinical manifestations. Epidemiology. Investigative techniques. Etiology ; Cognition ; Cohort Studies ; Complications and side effects ; Diagnosis ; Epidemiology ; Health Administration ; Health aspects ; Health Services for the Aged ; Humans ; Hypertension ; Magnetic Resonance Imaging ; Measurement ; Medical sciences ; Medicine ; Medicine & Public Health ; Office Visits ; original-article ; Patients ; Predictive Value of Tests ; Public Health ; Reproducibility ; Reproducibility of Results ; Sleep ; Time Factors</subject><ispartof>Journal of human hypertension, 2010-11, Vol.24 (11), p.749-754</ispartof><rights>Macmillan Publishers Limited 2010</rights><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2010 Nature Publishing Group</rights><rights>Macmillan Publishers Limited 2010.</rights><rights>Copyright Nature Publishing Group Nov 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c619t-bb1b3b18768271b2cf6f6ce5f3be5cbbe19ccb2d048b26034da65957de0cb82d3</citedby><cites>FETCH-LOGICAL-c619t-bb1b3b18768271b2cf6f6ce5f3be5cbbe19ccb2d048b26034da65957de0cb82d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/jhh.2010.8$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/jhh.2010.8$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23292451$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20200549$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Campbell, P</creatorcontrib><creatorcontrib>Ghuman, N</creatorcontrib><creatorcontrib>Wakefield, D</creatorcontrib><creatorcontrib>Wolfson, L</creatorcontrib><creatorcontrib>White, W B</creatorcontrib><title>Long-term reproducibility of ambulatory blood pressure is superior to office blood pressure in the very elderly</title><title>Journal of human hypertension</title><addtitle>J Hum Hypertens</addtitle><addtitle>J Hum Hypertens</addtitle><description>Although it is known that reproducibility of ambulatory blood pressure (BP) is superior to office BP in middle-aged subjects, little is known in older age groups. Hence, we compared the long-term reproducibility of ambulatory and office BP readings in subjects over the age of 75 years. A cohort of 72 subjects 75–90 years of age (mean, 82 years at baseline) had repeat office and ambulatory BPs 2 years apart under similar conditions. On the same day, patients underwent office BP measurements by a semi-automated device and then by ambulatory BP monitoring. Awake and sleep periods were divided according to a diary kept by each patient. The agreement between studies was assessed using the standard deviation of the differences (SDD) and Bland–Altman plots. There were minimal mean changes in office, 24-h, and awake and sleep mean BP values between baseline and 2 years later. The SDDs between visits were lower for 24-h BP compared with the office BP (11.7/5.9 mm Hg versus 17.8/9.0 mm Hg,
P
<0.01). The SDD for 24-h BP was also lower than the SDDs for the awake and sleep BP (
P
<0.05). Nocturnal BPs defined by absolute values were more reproducible than categories of dippers and non-dippers. These data demonstrate that long-term reproducibility of 24-h BP is superior to office measurements for very elderly subjects. In a clinical trial involving this age group, far fewer subjects would be required if 24-h BP was the primary efficacy endpoint rather than the office BP.</description><subject>692/699/75/243</subject><subject>692/700/139/1735</subject><subject>692/700/1518</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arterial hypertension. Arterial hypotension</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Blood Pressure</subject><subject>Blood Pressure Determination - methods</subject><subject>Blood Pressure Monitoring, Ambulatory</subject><subject>Brain - pathology</subject><subject>Cardiology. Vascular system</subject><subject>Circadian Rhythm</subject><subject>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</subject><subject>Cognition</subject><subject>Cohort Studies</subject><subject>Complications and side effects</subject><subject>Diagnosis</subject><subject>Epidemiology</subject><subject>Health Administration</subject><subject>Health aspects</subject><subject>Health Services for the Aged</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Magnetic Resonance Imaging</subject><subject>Measurement</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Office Visits</subject><subject>original-article</subject><subject>Patients</subject><subject>Predictive Value of Tests</subject><subject>Public Health</subject><subject>Reproducibility</subject><subject>Reproducibility of Results</subject><subject>Sleep</subject><subject>Time Factors</subject><issn>0950-9240</issn><issn>1476-5527</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp90t2L1DAQAPAiird3-uIfIEVRQemapE2bvgjH4Rcs-KLPIUmn2yxpsibpwf73puze7q1f9KG085uZdDpZ9gyjJUYle78ZhiVB6Yk9yBa4auqCUtI8zBaopahoSYUusssQNgjNQfY4uyCIIESrdpG5lbPrIoIfcw9b77pJaamNjrvc9bkY5WREdH6XS-Ncl289hDB5yHXIw7QFr53Po0u21wr-QDaPA-S3kPLBdODN7kn2qBcmwNPD_Sr78enj95svxerb568316tC1biNhZRYlhKzdFzSYElUX_e1AtqXEqiSEnCrlCQdqpgkNSqrTtS0pU0HSElGuvIq-7Cvu53kCJ0CG70wfOv1KPyOO6H5ecTqga_dLSeMsaYkqcCbQwHvfk4QIh91UGCMsOCmwBvKWFkx2iT54je5cZO36etmhJu6atuEXv4LkbpCdU1LTE5qLQxwbXuXzqbmxvw6_UaUihGc1PIvKl0djFo5C71O788SXt9LGECYOARnpqidDefw7R4q70Lw0B8HhhGfd42nXePzrnGW8PP7Iz7Su-VK4NUBiKCE6b2wSoeTK0naTTp3fbd3IYXsGvxpNv9ra0VMS3Ysl8gsWPkLWZb1GA</recordid><startdate>20101101</startdate><enddate>20101101</enddate><creator>Campbell, P</creator><creator>Ghuman, N</creator><creator>Wakefield, D</creator><creator>Wolfson, L</creator><creator>White, W B</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20101101</creationdate><title>Long-term reproducibility of ambulatory blood pressure is superior to office blood pressure in the very elderly</title><author>Campbell, P ; Ghuman, N ; Wakefield, D ; Wolfson, L ; White, W B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c619t-bb1b3b18768271b2cf6f6ce5f3be5cbbe19ccb2d048b26034da65957de0cb82d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>692/699/75/243</topic><topic>692/700/139/1735</topic><topic>692/700/1518</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Arterial hypertension. Arterial hypotension</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Blood Pressure</topic><topic>Blood Pressure Determination - methods</topic><topic>Blood Pressure Monitoring, Ambulatory</topic><topic>Brain - pathology</topic><topic>Cardiology. Vascular system</topic><topic>Circadian Rhythm</topic><topic>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</topic><topic>Cognition</topic><topic>Cohort Studies</topic><topic>Complications and side effects</topic><topic>Diagnosis</topic><topic>Epidemiology</topic><topic>Health Administration</topic><topic>Health aspects</topic><topic>Health Services for the Aged</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Magnetic Resonance Imaging</topic><topic>Measurement</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Office Visits</topic><topic>original-article</topic><topic>Patients</topic><topic>Predictive Value of Tests</topic><topic>Public Health</topic><topic>Reproducibility</topic><topic>Reproducibility of Results</topic><topic>Sleep</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Campbell, P</creatorcontrib><creatorcontrib>Ghuman, N</creatorcontrib><creatorcontrib>Wakefield, D</creatorcontrib><creatorcontrib>Wolfson, L</creatorcontrib><creatorcontrib>White, W B</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of human hypertension</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Campbell, P</au><au>Ghuman, N</au><au>Wakefield, D</au><au>Wolfson, L</au><au>White, W B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term reproducibility of ambulatory blood pressure is superior to office blood pressure in the very elderly</atitle><jtitle>Journal of human hypertension</jtitle><stitle>J Hum Hypertens</stitle><addtitle>J Hum Hypertens</addtitle><date>2010-11-01</date><risdate>2010</risdate><volume>24</volume><issue>11</issue><spage>749</spage><epage>754</epage><pages>749-754</pages><issn>0950-9240</issn><eissn>1476-5527</eissn><abstract>Although it is known that reproducibility of ambulatory blood pressure (BP) is superior to office BP in middle-aged subjects, little is known in older age groups. Hence, we compared the long-term reproducibility of ambulatory and office BP readings in subjects over the age of 75 years. A cohort of 72 subjects 75–90 years of age (mean, 82 years at baseline) had repeat office and ambulatory BPs 2 years apart under similar conditions. On the same day, patients underwent office BP measurements by a semi-automated device and then by ambulatory BP monitoring. Awake and sleep periods were divided according to a diary kept by each patient. The agreement between studies was assessed using the standard deviation of the differences (SDD) and Bland–Altman plots. There were minimal mean changes in office, 24-h, and awake and sleep mean BP values between baseline and 2 years later. The SDDs between visits were lower for 24-h BP compared with the office BP (11.7/5.9 mm Hg versus 17.8/9.0 mm Hg,
P
<0.01). The SDD for 24-h BP was also lower than the SDDs for the awake and sleep BP (
P
<0.05). Nocturnal BPs defined by absolute values were more reproducible than categories of dippers and non-dippers. These data demonstrate that long-term reproducibility of 24-h BP is superior to office measurements for very elderly subjects. In a clinical trial involving this age group, far fewer subjects would be required if 24-h BP was the primary efficacy endpoint rather than the office BP.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>20200549</pmid><doi>10.1038/jhh.2010.8</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | 692/699/75/243 692/700/139/1735 692/700/1518 Age Factors Aged Aged, 80 and over Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure Blood Pressure Determination - methods Blood Pressure Monitoring, Ambulatory Brain - pathology Cardiology. Vascular system Circadian Rhythm Clinical manifestations. Epidemiology. Investigative techniques. Etiology Cognition Cohort Studies Complications and side effects Diagnosis Epidemiology Health Administration Health aspects Health Services for the Aged Humans Hypertension Magnetic Resonance Imaging Measurement Medical sciences Medicine Medicine & Public Health Office Visits original-article Patients Predictive Value of Tests Public Health Reproducibility Reproducibility of Results Sleep Time Factors |
| title | Long-term reproducibility of ambulatory blood pressure is superior to office blood pressure in the very elderly |
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