Intermittent pneumatic leg compressions acutely upregulate VEGF and MCP-1 expression in skeletal muscle

Application of intermittent pneumatic compressions (IPC) is an extensively used therapeutic strategy in vascular medicine, but the mechanisms by which this method works are unclear. We tested the hypothesis that acute application (150 min) of cyclic leg compressions in a rat model signals upregulati...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2010-06, Vol.298 (6), p.H1991-H2000
Hauptverfasser:	Roseguini, Bruno T, Mehmet Soylu, S, Whyte, Jeffrey J, Yang, H T, Newcomer, Sean, Laughlin, M Harold
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Blood Pressure - physiology Chemokine CCL2 - metabolism Gene expression Intermittent Pneumatic Compression Devices Legs Male Models, Animal Muscle, Skeletal - blood supply Muscle, Skeletal - metabolism Musculoskeletal system Neovascularization, Physiologic - physiology Oxygen Consumption - physiology Physiology Proteins Rats Rats, Sprague-Dawley Regional Blood Flow - physiology Ribonucleic acid RNA RNA, Messenger - metabolism Rodents Up-Regulation - physiology Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism
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