Mice with a selective impairment of IFN-γ signaling in macrophage lineage cells demonstrate the critical role of IFN-γ activated macrophages for the control of protozoan parasitic infections in vivo1, 2
IFN-γ has long been recognized as a cytokine with potent and varied effects in the immune response. While its effects on specific cell types have been well studied in vitro , its in vivo effects are less clearly understood because of its diverse actions on many different cell types. While control of...
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Veröffentlicht in: | The Journal of immunology (1950) 2009-12, Vol.184 (2), p.877-885 |
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Hauptverfasser: | , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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