Mice with a selective impairment of IFN-γ signaling in macrophage lineage cells demonstrate the critical role of IFN-γ activated macrophages for the control of protozoan parasitic infections in vivo1, 2

IFN-γ has long been recognized as a cytokine with potent and varied effects in the immune response. While its effects on specific cell types have been well studied in vitro , its in vivo effects are less clearly understood because of its diverse actions on many different cell types. While control of...

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Veröffentlicht in:The Journal of immunology (1950) 2009-12, Vol.184 (2), p.877-885
Hauptverfasser: Lykens, Jennifer E., Terrell, Catherine E., Zoller, Erin E., Divanovic, Senad, Trompette, Aurelien, Karp, Christopher L., Aliberti, Julio, Flick, Matthew J., Jordan, Michael B.
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Sprache:eng
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