Enzymatic Digestion of Chronic Wasting Disease Prions Bound to Soil

Chronic wasting disease (CWD) and sheep scrapie can be transmitted via indirect environmental routes, and it is known that soil can serve as a reservoir of prion infectivity. Given the strong interaction between the prion protein (PrP) and soil, we hypothesized that binding to soil enhances prion re...

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Veröffentlicht in:	Environmental science & technology 2010-06, Vol.44 (11), p.4129-4135
Hauptverfasser:	Saunders, Samuel E, Bartz, Jason C, Vercauteren, Kurt C, Bartelt-Hunt, Shannon L
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidity Adsorption Animals Biodegradation chronic wasting disease Cricetinae decontamination disease reservoirs disease transmission Environmental Processes Environmental science enzymatic reactions Enzymes Prions scrapie Scrapie - metabolism Sheep Soil Soil adsorption Soil contamination Spongiform encephalopathies subtilisin Wasting Disease, Chronic - metabolism
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