Signaling mechanisms in skeletal muscle: Acute responses and chronic adaptations to exercise

Physical activity elicits physiological responses in skeletal muscle that result in a number of health benefits, in particular in disease states, such as type 2 diabetes. An acute bout of exercise/muscle contraction improves glucose homeostasis by increasing skeletal muscle glucose uptake, while chr...

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Veröffentlicht in:	IUBMB life 2008-03, Vol.60 (3), p.145-153
Hauptverfasser:	Röckl, Katja S.C., Witczak, Carol A., Goodyear, Laurie J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological AMP-Activated Protein Kinases AMPK Calcineurin - metabolism Calcium-Calmodulin-Dependent Protein Kinases - metabolism Cyclic AMP-Dependent Protein Kinases - metabolism Exercise Glucose - metabolism glucose uptake GTPase-Activating Proteins - metabolism Heat-Shock Proteins Humans Multienzyme Complexes - metabolism Muscle, Skeletal - cytology Muscle, Skeletal - physiology p38 Mitogen-Activated Protein Kinases - metabolism Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Protein Kinase C - metabolism Protein-Serine-Threonine Kinases - metabolism Signal Transduction - physiology skeletal muscle training adaptation Transcription Factors
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