The Effects of Piroxicam in the Attenuation of MPP+/MPTP Toxicity In Vitro and In Vivo

Several lines of evidence support the neuroprotective action of cyclooxygenase-2 (COX-2) inhibitors in various models of Parkinson’s disease (PD). In the current study, we investigated the neuroprotective properties of several COX inhibitors against 1-methyl-4-phenylpyridinium (MPP+) in neuroblastom...

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Veröffentlicht in:	Neurochemical research 2009-02, Vol.34 (2), p.304-310
Hauptverfasser:	Soliman, Y., Jackson, T., Mazzio, E., Soliman, K. F. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyl-4-phenylpyridinium - toxicity Adenosine Triphosphate - metabolism Animals Biochemistry Biomedical and Life Sciences Biomedicine Blotting, Western Cell Biology Chromatography, High Pressure Liquid Cyclooxygenase Inhibitors - pharmacology Cyclooxygenase Inhibitors - therapeutic use In Vitro Techniques Male Mice Mice, Inbred C57BL Mitochondria - metabolism Motor Activity MPTP Poisoning - drug therapy Neurochemistry Neurology Neurosciences Original Paper Oxygen - metabolism Piroxicam - pharmacology Piroxicam - therapeutic use
Online-Zugang:	Volltext
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