Subcellular localization and dynamics of Mac-1 (αmβ2) in human neutrophils

The subcellular localization of Mac-1 was determined in resting and stimulated human neutrophils after disruption by nitrogen cavitation and fractionation on two-layer Percoll density gradients. Light membranes were further separated by high voltage free flow electrophoresis. Mac-1 was determined by...

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Veröffentlicht in:	The Journal of clinical investigation 1993-09, Vol.92 (3), p.1467-1476
Hauptverfasser:	SENGELØV, H, KJELDSEN, L, DIAMOND, M. S, SPRINGER, T. A, BORREGAARD, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Compartmentation Cell Membrane - metabolism Cell physiology Cytoplasmic Granules - metabolism Fundamental and applied biological sciences. Psychology Humans In Vitro Techniques Macrophage-1 Antigen - metabolism Membrane and intracellular transports Molecular and cellular biology N-Formylmethionine Leucyl-Phenylalanine - pharmacology Neutrophils - metabolism Neutrophils - ultrastructure Subcellular Fractions - chemistry
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