Mechanisms of HDA6-mediated rRNA gene silencing: suppression of intergenic Pol II transcription and differential effects on maintenance versus siRNA-directed cytosine methylation

The Arabidopsis histone deacetylase HDA6 is required to silence transgenes, transposons, and ribosomal RNA (rRNA) genes subjected to nucleolar dominance in genetic hybrids. In nonhybrid Arabidopsis thaliana, we show that a class of 45S rRNA gene variants that is normally inactivated during developme...

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Veröffentlicht in:	Genes & development 2010-06, Vol.24 (11), p.1119-1132
Hauptverfasser:	Earley, Keith W, Pontvianne, Frédéric, Wierzbicki, Andrzej T, Blevins, Todd, Tucker, Sarah, Costa-Nunes, Pedro, Pontes, Olga, Pikaard, Craig S
Format:	Artikel
Sprache:	eng
Schlagworte:	Arabidopsis Proteins - genetics Arabidopsis Proteins - metabolism Cytosine - metabolism DNA Polymerase II - metabolism DNA, Intergenic - metabolism DNA-Directed DNA Polymerase - metabolism Gene Expression Regulation, Plant Gene Silencing Genes, rRNA - genetics Histone Deacetylases - genetics Histone Deacetylases - metabolism Histones - metabolism Methylation Mutation Research Paper RNA, Small Interfering - metabolism
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