Dual Sites of Protein Initiation Control the Localization and Myristoylation of Methionine Sulfoxide Reductase A

Methionine sulfoxide reductase A is an essential enzyme in the antioxidant system, which scavenges reactive oxygen species through cyclic oxidation and reduction of methionine and methionine sulfoxide. In mammals, one gene encodes two forms of the reductase, one targeted to the cytosol and the other...

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Veröffentlicht in:The Journal of biological chemistry 2010-06, Vol.285 (23), p.18085-18094
Hauptverfasser: Kim, Geumsoo, Cole, Nelson B., Lim, Jung Chae, Zhao, Hang, Levine, Rodney L.
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Sprache:eng
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