Characterization and Serologic Analysis of the Treponema pallidum Proteome

Treponema pallidum subsp. pallidum is the causative agent of syphilis, a sexually transmitted disease characterized by widespread tissue dissemination and chronic infection. In this study, we analyzed the proteome of T. pallidum by the isoelectric focusing (IEF) and nonequilibrating pH gel electroph...

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Veröffentlicht in:	Infection and Immunity 2010-06, Vol.78 (6), p.2631-2643
Hauptverfasser:	McGill, Melanie A, Edmondson, Diane G, Carroll, James A, Cook, Richard G, Orkiszewski, Ralph S, Norris, Steven J
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Antibodies, Bacterial - blood Antibody response Antigens, Bacterial - analysis Antigens, Bacterial - chemistry Antigens, Bacterial - immunology Bacterial Proteins - analysis Bacterial Proteins - chemistry Bacterial Proteins - immunology Bacteriology Biological and medical sciences Blotting, Western Chronic infection Combined vaccines Electrophoresis, Gel, Two-Dimensional Flagellin Flight Fundamental and applied biological sciences. Psychology Gel electrophoresis Globus pallidus Host-pathogen interactions Humans Isoelectric Focusing Lasers Lipoproteins Mice Mice, Inbred BALB C Microbiology Miscellaneous Molecular Pathogenesis Molecular Weight pH effects Proteins Proteome - analysis proteomics Rabbits Sexually-transmitted diseases Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Syphilis Syphilis - immunology Treponema pallidum Treponema pallidum - chemistry Treponema pallidum - immunology
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