Regulation of p53 expression, phosphorylation and sub-cellular localisation by a G-protein coupled receptor

G-protein coupled receptors (GPCRs) have been extremely successful drug targets for a multitude of diseases from heart failure to depression. This super-family of cell surface receptors have not, however, been widely considered as a viable target in cancer treatment. In the current study we demonstr...

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Veröffentlicht in:	Oncogene 2009-08, Vol.28 (41), p.3619-3630
Hauptverfasser:	Solyakov, Lev, Sayan, Emre, Riley, Joan, Pointon, Amy, Tobin, Andrew B
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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