Integrated stoichiometric, thermodynamic and kinetic modelling of steady state metabolism

The quantitative analysis of biochemical reactions and metabolites is at frontier of biological sciences. The recent availability of high-throughput technology data sets in biology has paved the way for new modelling approaches at various levels of complexity including the metabolome of a cell or an...

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Veröffentlicht in:	Journal of theoretical biology 2010-06, Vol.264 (3), p.683-692
Hauptverfasser:	Fleming, R.M.T., Thiele, I., Provan, G., Nasheuer, H.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algebraic geometry Algorithms Bacterial Physiological Phenomena Computational Biology Computer Simulation Constraint-based modelling Energy Metabolism - physiology Escherichia coli Escherichia coli - metabolism Escherichia coli - physiology Kinetics Linear polytope Logarithmic polytope Models, Biological Systems biology Thermodynamics
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