N-cadherin mediates plasticity-induced long-term spine stabilization

Excitatory synapses on dendritic spines are dynamic structures whose stability can vary from hours to years. However, the molecular mechanisms regulating spine persistence remain essentially unknown. In this study, we combined repetitive imaging and a gain and loss of function approach to test the r...

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Veröffentlicht in:The Journal of cell biology 2010-05, Vol.189 (3), p.589-600
Hauptverfasser: Mendez, Pablo, De Roo, Mathias, Poglia, Lorenzo, Klauser, Paul, Muller, Dominique
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Sprache:eng
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