The Mechanism Whereby Heat Shock Induces Apoptosis Depends on the Innate Sensitivity of Cells to Stress

The cellular response to heat shock (HS) is a paradigm for many human diseases collectively known as "protein conformation diseases" in which the accumulation of misfolded proteins induces cell death. Here, we analyzed how cells having a different apoptotic threshold die subsequent to a tr...

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Veröffentlicht in:Cell stress & chaperones 2010-01, Vol.15 (1), p.101-113
Hauptverfasser: Bellmann, Kerstin, Charette, Steve J., Nadeau, Philippe J., Poirier, Dominic J., Loranger, Anne, Landry, Jacques
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Sprache:eng
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