Monoclonal Antibody to Novel Cell Surface Epitope on Hsc70 Promotes Morphogenesis of Bile Ducts in Newborn Rat Liver

We previously described a cell surface reactive monoclonal antibody, MAb OC.10, which recognizes an epitope shared by rat fetal liver ductal cells, hepatic progenitor cells, mature cholangiocytes, and hepatocellular carcinomas (HCC). Here, intrasplenic injection of MAb OC.10 into newborn rats was sh...

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Veröffentlicht in:	Cell stress & chaperones 2010-01, Vol.15 (1), p.39-53
Hauptverfasser:	Mills, David R., Haskell, Michelle D., Callanan, Helen M., Flanagan, Donna L., Brilliant, Kate E., Yang, DongQin, Hixson, Douglas C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Animals, Newborn Antibodies Antibodies, Monoclonal - immunology Antibodies, Monoclonal - metabolism Antibodies, Monoclonal - pharmacology Bile ducts Bile Ducts, Intrahepatic - growth & development Biochemistry Biomedical and Life Sciences Biomedicine Cancer Research Cell Biology Cell membranes Cells, Cultured Cellular immunity Epithelial cells Epitope Mapping Epitopes Epitopes - immunology Epitopes - metabolism Hepatocytes HSP70 Heat-Shock Proteins - immunology HSP70 Heat-Shock Proteins - metabolism Humans Immunology Liver Liver - growth & development Molecular Sequence Data Morphogenesis Natural killer cells Neurosciences Original Paper Protein Structure, Tertiary Rats Reactivity RNA, Small Interfering - metabolism
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