Quantal release of acetylcholine in mice with reduced levels of the vesicular acetylcholine transporter

J. Neurochem. (2010) 113, 943-951. Mammalian motor nerve terminals contain hundreds of thousands of synaptic vesicles, but only a fraction of these vesicles is immediately available for release, the remainder forming a reserve pool. The supply of vesicles is replenished through endocytosis, and newl...

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Veröffentlicht in:	Journal of neurochemistry 2010-05, Vol.113 (4), p.943-951
Hauptverfasser:	Lima, Ricardo de Freitas, Prado, Vania F, Prado, Marco A.M, Kushmerick, Christopher
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine Acetylcholine - metabolism Acetylcholine - secretion Adult and adolescent clinical studies Animals Biochemistry Biological and medical sciences Calcium - metabolism Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Depression Down-Regulation - drug effects Down-Regulation - physiology Electric Stimulation Excitatory Postsynaptic Potentials - drug effects Excitatory Postsynaptic Potentials - physiology Fundamental and applied biological sciences. Psychology Magnesium - metabolism Medical sciences MEPP Mice Mice, Transgenic Mood disorders Motor Neurons - metabolism Motor Neurons - secretion Motor Neurons - ultrastructure Muscle, Skeletal - innervation Muscle, Skeletal - physiology Neurology neuromuscular junction Neuromuscular Junction - metabolism Neuromuscular Junction - secretion Neuromuscular Junction - ultrastructure Neuronal Plasticity - physiology Neurotransmitters post-tetanic potentiation Presynaptic Terminals - metabolism Presynaptic Terminals - secretion Presynaptic Terminals - ultrastructure Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry quantal content Rodents Synaptic Transmission - drug effects Synaptic Transmission - physiology synaptic vesicle Synaptic Vesicles - metabolism Synaptic Vesicles - secretion Transgenic animals Vertebrates: nervous system and sense organs Vesicular Acetylcholine Transport Proteins - genetics Vesicular Acetylcholine Transport Proteins - metabolism
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