Anucleate platelets generate progeny

Platelets are classified as terminally differentiated cells that are incapable of cellular division. However, we observe that anucleate human platelets, either maintained in suspension culture or captured in microdrops, give rise to new cell bodies packed with respiring mitochondria and α-granules....

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Veröffentlicht in:	Blood 2010-05, Vol.115 (18), p.3801-3809
Hauptverfasser:	Schwertz, Hansjörg, Köster, Sarah, Kahr, Walter H.A., Michetti, Noemi, Kraemer, Bjoern F., Weitz, David A., Blaylock, Robert C., Kraiss, Larry W., Greinacher, Andreas, Zimmerman, Guy A., Weyrich, Andrew S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Annexin A5 - metabolism Biological and medical sciences Biomarkers Blood Platelets - cytology Blood Platelets - metabolism Blood Platelets - ultrastructure Cell Proliferation Electrophoresis, Gel, Two-Dimensional Hematologic and hematopoietic diseases Humans Medical sciences P-Selectin - metabolism Platelet Aggregation Platelet Count Platelets and Thrombopoiesis Thrombopoiesis
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