CNS Depressant Activity of Ethanol Extract of Sterculia guttata seeds in mice

CNS Depressant Activity of Ethanol Extract of Sterculia guttata seeds in mice

Shade dried, powdered seeds of Sterculia guttata were extracted using a Soxhlet extractor with ethanol. Ethanol was removed under reduced pressure and dried to obtained crude extract. This extract was evaluated for its effect on behavioral changes, exploratory activity and barbiturate-sleeping time,...

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Veröffentlicht in:Indian journal of pharmaceutical sciences 2009-07, Vol.71 (4), p.445-447
Hauptverfasser: Katade, S R, Misar, A V, Mujumdar, A M, Phalgune, U D, Wakharkar, R D, Deshpande, N R
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Central nervous system
Enzymes
Folk medicine
Health aspects
Materia medica, Vegetable
Physiological aspects
Plant extracts
Rodents
Short Communication
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Zusammenfassung:Shade dried, powdered seeds of Sterculia guttata were extracted using a Soxhlet extractor with ethanol. Ethanol was removed under reduced pressure and dried to obtained crude extract. This extract was evaluated for its effect on behavioral changes, exploratory activity and barbiturate-sleeping time, using appropriate standard methods in mice. The extract exhibited dose-dependent CNS depressant activity.
ISSN:0250-474X
1998-3743
DOI:10.4103/0250-474X.57297