Acute Modulation of Sugar Transport in Brain Capillary Endothelial Cell Cultures during Activation of the Metabolic Stress Pathway

GLUT1-catalyzed equilibrative sugar transport across the mammalian blood-brain barrier is stimulated during acute and chronic metabolic stress; however, the mechanism of acute transport regulation is unknown. We have examined acute sugar transport regulation in the murine brain microvasculature endo...

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Veröffentlicht in:	The Journal of biological chemistry 2010-05, Vol.285 (20), p.15430-15439
Hauptverfasser:	Cura, Anthony J., Carruthers, Anthony
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism AMP-activated kinase (AMPK) Animals Base Sequence Brain - blood supply Brain Metabolism Capillaries - cytology Capillaries - drug effects Capillaries - metabolism Carbohydrate Metabolism Cell Biology Cell Line Cytochalasin B - pharmacology DNA Primers Endothelium, Vascular - cytology Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Membrane Biology Membrane Biophysics Membrane Proteins Membrane Trafficking Mice Oxidative Stress Phosphorylation Reverse Transcriptase Polymerase Chain Reaction Transport Sugars
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