Neurogenesis and Alzheimer's disease: At the crossroads

While a massive and progressive neuronal loss in specific areas such as the hippocampus and cortex unequivocally underlies cognitive deterioration and memory loss in Alzheimer's disease, noteworthy alterations take place in the neurogenic microenvironments, namely, the subgranule layer of the d...

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Veröffentlicht in:	Experimental neurology 2010-06, Vol.223 (2), p.267-281
Hauptverfasser:	Lazarov, Orly, Marr, Robert A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - pathology Alzheimer Disease - physiopathology Alzheimer's disease Amyloid precursor protein Brain - pathology Brain - physiopathology Brain plasticity Humans LDL receptors Neurogenesis Neurogenesis - physiology Presenilin Stem cells Tau
Online-Zugang:	Volltext
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