HIV integration site distributions in resting and activated CD4+ T cells infected in culture

The goal of this study was to investigate whether the location of HIV integration differs in resting versus activated T cells, a feature that could contribute to the formation of latent viral reservoirs via effects on integration targeting. Primary resting or activated CD4 T cells were infected with...

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Veröffentlicht in:AIDS (London) 2009-07, Vol.23 (12), p.1461-1471
Hauptverfasser: BRADY, Troy, AGOSTO, Luis M, MALANI, Nirav, BERRY, Charles C, O'DOHERTY, Una, BUSHMAN, Frederic
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Sprache:eng
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