Adaptor protein 2 regulates receptor-mediated endocytosis and cyst formation in Giardia lamblia

The parasite Giardia lamblia possesses PVs (peripheral vacuoles) that function as both endosomes and lysosomes and are implicated in the adaptation, differentiation and survival of the parasite in different environments. The mechanisms by which Giardia traffics essential proteins to these organelles...

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Veröffentlicht in:	Biochemical journal 2010-05, Vol.428 (1), p.33-45
Hauptverfasser:	Rivero, Maria R, Vranych, Cecilia V, Bisbal, Mariano, Maletto, Belkys A, Ropolo, Andrea S, Touz, Maria C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Protein Complex 2 - chemistry Adaptor Protein Complex 2 - genetics Adaptor Protein Complex 2 - metabolism Animals Antibodies, Monoclonal - immunology Cell Membrane - metabolism Down-Regulation Endocytosis - physiology Endosomes - metabolism Fluorescent Antibody Technique Giardia lamblia - growth & development Mice Mice, Inbred BALB C Models, Molecular Protein Conformation Proteins - metabolism Protozoan Proteins - chemistry Protozoan Proteins - genetics Protozoan Proteins - metabolism
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