High-Performance Single Cell Genetic Analysis Using Microfluidic Emulsion Generator Arrays

High-throughput genetic and phenotypic analysis at the single cell level is critical to advance our understanding of the molecular mechanisms underlying cellular function and dysfunction. Here we describe a high-performance single cell genetic analysis (SCGA) technique that combines high-throughput...

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Veröffentlicht in:	Analytical chemistry (Washington) 2010-04, Vol.82 (8), p.3183-3190
Hauptverfasser:	Zeng, Yong, Novak, Richard, Shuga, Joe, Smith, Martyn T, Mathies, Richard A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Cells Chemistry Escherichia coli - genetics Escherichia coli - isolation & purification Exact sciences and technology Genetics Genotype & phenotype High-Throughput Screening Assays Microemulsions Microfluidic Analytical Techniques - methods Molecular structure Polymerase Chain Reaction
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