Curvature variation along the tropomyosin molecule

Complementarity between the tropomyosin supercoil and the helical contour of actin-filaments is required for the binding interaction of actin and tropomyosin (Li et al., 2010). Clusters of small alanine residues in place of canonical leucines along coiled-coil tropomyosin may be responsible for pre-...

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Veröffentlicht in:	Journal of structural biology 2010-05, Vol.170 (2), p.307-312
Hauptverfasser:	Li, Xiaochuan (Edward), Lehman, William, Fischer, Stefan, Holmes, Kenneth C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actins - chemistry Actins - metabolism Alanine - chemistry Amino Acid Sequence Coiled-coils Crystallography, X-Ray Electron microscopy Models, Molecular Molecular dynamics Molecular Dynamics Simulation Molecular Sequence Data Protein Conformation Tropomyosin Tropomyosin - chemistry Tropomyosin - metabolism
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