c-Myb promotes the survival of CD4+CD8+ double positive thymocytes through up-regulation of Bcl-xL

Mechanisms that regulate the lifespan of CD4 + CD8 + double positive (DP) thymocytes help shape the peripheral T cell repertoire. However, the molecular mechanisms that control DP thymocyte survival remain poorly understood. The Myb proto-oncogene encodes a transcription factor required during multi...

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Veröffentlicht in:	The Journal of immunology (1950) 2010-02, Vol.184 (6), p.2793-2804
Hauptverfasser:	Yuan, Joan, Crittenden, Rowena B., Bender, Timothy P.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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