Unfolded-State Dynamics and Structure of Protein L Characterized by Simulation and Experiment

While several experimental techniques now exist for characterizing protein unfolded states, all-atom simulation of unfolded states has been challenging due to the long time scales and conformational sampling required. We address this problem by using a combination of accelerated calculations on grap...

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Veröffentlicht in:	Journal of the American Chemical Society 2010-04, Vol.132 (13), p.4702-4709
Hauptverfasser:	Voelz, Vincent A, Singh, Vijay R, Wedemeyer, William J, Lapidus, Lisa J, Pande, Vijay S
Format:	Artikel
Sprache:	eng
Schlagworte:	Calibration Models, Molecular Molecular Dynamics Simulation Protein Conformation Protein Denaturation Protein Folding Proteins - chemistry Temperature Thermodynamics
Online-Zugang:	Volltext
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