Inhalational anaesthetics and n‐alcohols share a site of action in the neuronal Shaw2 Kv channel

Background and purpose:  Neuronal ion channels are key targets of general anaesthetics and alcohol, and binding of these drugs to pre‐existing and relatively specific sites is thought to alter channel gating. However, the underlying molecular mechanisms of this action are still poorly understood. He...

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Veröffentlicht in:British journal of pharmacology 2010-04, Vol.159 (7), p.1475-1485
Hauptverfasser: Bhattacharji, Aditya, Klett, Nathan, Go, Ramon Christopher V, Covarrubias, Manuel
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Sprache:eng
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