Mechanisms of Enhanced β-Adrenergic Reserve From Cardiac Resynchronization Therapy

Cardiac resynchronization therapy (CRT) is the first clinical heart failure treatment that improves chamber systolic function in both the short-term and long-term yet also reduces mortality. The mechanical impact of CRT is immediate and well documented, yet its long-term influences on myocyte functi...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2009-03, Vol.119 (9), p.1231-1240
Hauptverfasser:	CHAKIR, Khalid, DAYA, Samantapudi K, XIAO, Rui-Ping, TOMASELLI, Gordon F, KASS, David A, AIBA, Takeshi, TUNIN, Richard S, DIMAANO, Veronica L, ABRAHAM, Theodore P, JACQUES, Kathryn, LAI, Edwin W, PACAK, Karel, ZHU, Wei-Zhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - metabolism Animals Biological and medical sciences Blood and lymphatic vessels Blood. Blood coagulation. Reticuloendothelial system Cardiology. Vascular system Catecholamines - metabolism Colforsin - pharmacology Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Dogs GTP-Binding Protein alpha Subunits, Gi-Go - metabolism Heart Failure - metabolism Heart Failure - physiopathology Heart Failure - therapy Medical sciences Myocardial Contraction - physiology Myocytes, Cardiac - drug effects Myocytes, Cardiac - physiology Pacemaker, Artificial Pharmacology. Drug treatments Radioligand Assay Receptors, Adrenergic, beta-1 - physiology Receptors, Adrenergic, beta-2 - physiology RGS Proteins - physiology Sarcomeres - physiology Signal Transduction - physiology
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