A new genetic model of activity-induced Ras signaling dependent pre-synaptic plasticity in Drosophila

Abstract Techniques to induce activity-dependent neuronal plasticity in vivo allow the underlying signaling pathways to be studied in their biological context. Here, we demonstrate activity-induced plasticity at neuromuscular synapses of Drosophila double mutant for comatose (an NSF mutant) and Kum...

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Veröffentlicht in:	Brain research 2010-04, Vol.1326, p.15-29
Hauptverfasser:	Freeman, Amanda, Bowers, Mallory, Mortimer, Alysia Vrailas, Timmerman, Christina, Roux, Stephanie, Ramaswami, Mani, Sanyal, Subhabrata
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Biological and medical sciences Cell physiology Coma - genetics CREB-Binding Protein - genetics CREB-Binding Protein - metabolism Drosophila Drosophila - genetics Drosophila Proteins - genetics Drosophila Proteins - metabolism Enzyme Activation - genetics Fos Fundamental and applied biological sciences. Psychology Gene Expression Regulation - genetics Models, Animal Molecular and cellular biology Neurology Neuromuscular Junction - genetics Neuron Neuronal Plasticity - genetics Plasticity Ras ras Proteins - genetics Signal transduction Signal Transduction - genetics Synapse Transcription Factor AP-1 - genetics Transcription Factor AP-1 - metabolism
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