Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2010-04, Vol.54 (4), p.1476-1483 |
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creator | MACCALLUM, Donna M COSTE, Alix ISCHER, Françoise JACOBSEN, Mette D ODDS, Frank C SANGLARD, Dominique |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.01645-09</identifier><identifier>PMID: 20086148</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Animals ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antifungal Agents ; Antifungal Agents - pharmacology ; Base Sequence ; Biological and medical sciences ; Candida albicans ; Candida albicans - drug effects ; Candida albicans - genetics ; Candida albicans - isolation & purification ; Candida albicans - pathogenicity ; Candidiasis ; Candidiasis - drug therapy ; Candidiasis - microbiology ; Disease Models, Animal ; DNA Primers - genetics ; DNA, Fungal - genetics ; Drug Resistance, Fungal ; Drug Resistance, Fungal - genetics ; Experimental Therapeutics ; Female ; Fluconazole ; Fluconazole - pharmacology ; Fungal Proteins - genetics ; Genes, Fungal ; Genetic Engineering ; Humans ; In Vitro Techniques ; Medical sciences ; Membrane Transport Proteins - genetics ; Mice ; Mice, Inbred BALB C ; Microbial Sensitivity Tests ; Mutation ; Pharmacology. Drug treatments</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2010-04, Vol.54 (4), p.1476-1483</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2010 American Society for Microbiology</rights><rights>Copyright © 2010, American Society for Microbiology 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a505t-140bf04cea4e9bb0a057e039ca4e8cf0ab58fa46eb4f101e4e7723da83e9c99b3</citedby><cites>FETCH-LOGICAL-a505t-140bf04cea4e9bb0a057e039ca4e8cf0ab58fa46eb4f101e4e7723da83e9c99b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849354/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849354/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22546006$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20086148$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MACCALLUM, Donna M</creatorcontrib><creatorcontrib>COSTE, Alix</creatorcontrib><creatorcontrib>ISCHER, Françoise</creatorcontrib><creatorcontrib>JACOBSEN, Mette D</creatorcontrib><creatorcontrib>ODDS, Frank C</creatorcontrib><creatorcontrib>SANGLARD, Dominique</creatorcontrib><title>Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Animals</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antifungal Agents</subject><subject>Antifungal Agents - pharmacology</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>Candida albicans</subject><subject>Candida albicans - drug effects</subject><subject>Candida albicans - genetics</subject><subject>Candida albicans - isolation & purification</subject><subject>Candida albicans - pathogenicity</subject><subject>Candidiasis</subject><subject>Candidiasis - drug therapy</subject><subject>Candidiasis - microbiology</subject><subject>Disease Models, Animal</subject><subject>DNA Primers - genetics</subject><subject>DNA, Fungal - genetics</subject><subject>Drug Resistance, Fungal</subject><subject>Drug Resistance, Fungal - genetics</subject><subject>Experimental Therapeutics</subject><subject>Female</subject><subject>Fluconazole</subject><subject>Fluconazole - pharmacology</subject><subject>Fungal Proteins - genetics</subject><subject>Genes, Fungal</subject><subject>Genetic Engineering</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>Medical sciences</subject><subject>Membrane Transport Proteins - genetics</subject><subject>Mice</subject><subject>Mice, Inbred BALB C</subject><subject>Microbial Sensitivity Tests</subject><subject>Mutation</subject><subject>Pharmacology. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Antifungal Agents</topic><topic>Antifungal Agents - pharmacology</topic><topic>Base Sequence</topic><topic>Biological and medical sciences</topic><topic>Candida albicans</topic><topic>Candida albicans - drug effects</topic><topic>Candida albicans - genetics</topic><topic>Candida albicans - isolation & purification</topic><topic>Candida albicans - pathogenicity</topic><topic>Candidiasis</topic><topic>Candidiasis - drug therapy</topic><topic>Candidiasis - microbiology</topic><topic>Disease Models, Animal</topic><topic>DNA Primers - genetics</topic><topic>DNA, Fungal - genetics</topic><topic>Drug Resistance, Fungal</topic><topic>Drug Resistance, Fungal - genetics</topic><topic>Experimental Therapeutics</topic><topic>Female</topic><topic>Fluconazole</topic><topic>Fluconazole - pharmacology</topic><topic>Fungal Proteins - genetics</topic><topic>Genes, Fungal</topic><topic>Genetic Engineering</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>Medical sciences</topic><topic>Membrane Transport Proteins - genetics</topic><topic>Mice</topic><topic>Mice, Inbred BALB C</topic><topic>Microbial Sensitivity Tests</topic><topic>Mutation</topic><topic>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>20086148</pmid><doi>10.1128/AAC.01645-09</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal Agents Antifungal Agents - pharmacology Base Sequence Biological and medical sciences Candida albicans Candida albicans - drug effects Candida albicans - genetics Candida albicans - isolation & purification Candida albicans - pathogenicity Candidiasis Candidiasis - drug therapy Candidiasis - microbiology Disease Models, Animal DNA Primers - genetics DNA, Fungal - genetics Drug Resistance, Fungal Drug Resistance, Fungal - genetics Experimental Therapeutics Female Fluconazole Fluconazole - pharmacology Fungal Proteins - genetics Genes, Fungal Genetic Engineering Humans In Vitro Techniques Medical sciences Membrane Transport Proteins - genetics Mice Mice, Inbred BALB C Microbial Sensitivity Tests Mutation Pharmacology. Drug treatments |
title | Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection |
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