Sensitization, Duration, and Pharmacological Blockade of Anxiety-Like Behavior Following Repeated Ethanol Withdrawal in Adolescent and Adult Rats

Background: Repeated ethanol withdrawal sensitizes anxiety‐like behavior in adult rats and causes anxiety‐like behavior and decreased seizure thresholds in adolescent rats. Current experiments determined if adolescent rats exhibit sensitized anxiety‐like behavior, the duration of this effect, if dr...

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Veröffentlicht in:	Alcoholism, clinical and experimental research clinical and experimental research, 2009-03, Vol.33 (3), p.455-463
Hauptverfasser:	Wills, Tiffany A., Knapp, Darin J., Overstreet, David H., Breese, George R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescents Aging - blood Aging - psychology Alcohol Drinking Alcoholism and acute alcohol poisoning Animals Anxiety Anxiety - etiology Anxiety - prevention & control Biological and medical sciences Buspirone - therapeutic use Central Nervous System Depressants - administration & dosage Central Nervous System Depressants - blood Development Ethanol - administration & dosage Ethanol - blood Flumazenil - therapeutic use GABA Modulators - therapeutic use Male Medical sciences Rats Rats, Sprague-Dawley Repeated Ethanol Withdrawal Sensitization Serotonin Receptor Agonists - therapeutic use Substance Withdrawal Syndrome - psychology Time Factors Toxicology
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