Mapping Alzheimer's disease progression in 1309 MRI scans: Power estimates for different inter-scan intervals

Neuroimaging centers and pharmaceutical companies are working together to evaluate treatments that might slow the progression of Alzheimer's disease (AD), a common but devastating late-life neuropathology. Recently, automated brain mapping methods, such as tensor-based morphometry (TBM) of stru...

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Veröffentlicht in:	NeuroImage (Orlando, Fla.) Fla.), 2010-05, Vol.51 (1), p.63-75
Hauptverfasser:	Hua, Xue, Lee, Suh, Hibar, Derrek P., Yanovsky, Igor, Leow, Alex D., Toga, Arthur W., Jack, Clifford R., Bernstein, Matt A., Reiman, Eric M., Harvey, Danielle J., Kornak, John, Schuff, Norbert, Alexander, Gene E., Weiner, Michael W., Thompson, Paul M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging Alzheimer Disease - pathology Alzheimer's disease Automation Brain - pathology Brain Mapping - methods Clinical trials Cognition Disorders - pathology Confidence intervals Databases, Factual Disease Progression Estimates Female Humans Imaging, Three-Dimensional - methods Longitudinal Studies Magnetic Resonance Imaging - methods Male Medical imaging Studies Temporal Lobe - pathology Time Factors
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