Doc2b Is a High-Affinity Ca²⁺ Sensor for Spontaneous Neurotransmitter Release

Synaptic vesicle fusion in brain synapses occurs in phases that are either tightly coupled to action potentials (synchronous), immediately following action potentials (asynchronous), or as stochastic events in the absence of action potentials (spontaneous). Synaptotagmin-1, -2, and -9 are vesicle-as...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 2010-03, Vol.327 (5973), p.1614-1618
Hauptverfasser:	Groffen, Alexander J, Martens, Sascha, Arazola, Rocío Díez, Cornelisse, L. Niels, Lozovaya, Natalia, de Jong, Arthur P.H, Goriounova, Natalia A, Habets, Ron L.P, Takai, Yoshimi, Borst, J. Gerard, Brose, Nils, McMahon, Harvey T, Verhage, Matthijs
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Animals Beta cells Binding Sites Biological and medical sciences Brain Calcium - metabolism Calcium-Binding Proteins - chemistry Calcium-Binding Proteins - genetics Calcium-Binding Proteins - metabolism Cells, Cultured Cellular biology Chromaffin cells Excitatory Postsynaptic Potentials Fundamental and applied biological sciences. Psychology Hippocampus - cytology Inhibitory Postsynaptic Potentials Liposomes Membrane Fusion Mice Mice, Knockout Mutant Proteins - genetics Mutant Proteins - metabolism Nerve Tissue Proteins - chemistry Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Neurons Neurons - physiology Neurotransmitter Agents - metabolism Neurotransmitters P branes Patch-Clamp Techniques Protein Structure, Tertiary Proteins Purkinje cells Purkinje Cells - physiology Rats Research Article Sensors SNARE proteins SNARE Proteins - metabolism Synapses Synaptic Transmission Synaptic Vesicles - physiology Synaptotagmin I - metabolism Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!