GATA4 Is Essential for Jejunal Function in Mice

Background & Aims Although the zinc-finger transcription factor GATA4 has been implicated in regulating jejunal gene expression, the contribution of GATA4 in controlling jejunal physiology has not been addressed. Methods We generated mice in which the Gata4 gene was specifically deleted in the s...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2008-11, Vol.135 (5), p.1676-1686.e1
Hauptverfasser:	Battle, Michele A, Bondow, Benjamin J, Iverson, Moriah A, Adams, Scott J, Jandacek, Ronald J, Tso, Patrick, Duncan, Stephen A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cholesterol, Dietary - pharmacokinetics Dietary Fats - pharmacokinetics DNA - genetics Enterocytes - cytology Enterocytes - metabolism Gastroenterology and Hepatology GATA4 Transcription Factor - biosynthesis GATA4 Transcription Factor - genetics Gene Expression Ileum - cytology Ileum - physiology Immunohistochemistry Intestinal Absorption - physiology Jejunum - cytology Jejunum - physiology Mice Reverse Transcriptase Polymerase Chain Reaction Zinc Fingers
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