Mitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function

The mitochondrion is a major source of reactive oxygen species (ROS). Superoxide (O(2)(*-)) is generated under specific bioenergetic conditions at several sites within the electron-transport system; most is converted to H(2)O(2) inside and outside the mitochondrial matrix by superoxide dismutases. H...

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Veröffentlicht in:	Antioxidants & redox signaling 2009-06, Vol.11 (6), p.1373-1414
Hauptverfasser:	Stowe, David F, Camara, Amadou K S
Format:	Artikel
Sprache:	eng
Schlagworte:	Active oxygen Animals Comprehensive Invited Reviews Genetic aspects Humans Ion channels Mitochondria - metabolism Models, Biological Oxidation-Reduction Physiological aspects Reactive Oxygen Species - metabolism Superoxide dismutase Superoxides - metabolism
Online-Zugang:	Volltext
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