Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia

Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia

We report a case of progressive multifocal leukoencephalopathy developing in a fludarabine-naïve patient with chronic lymphocytic leukemia. We suggest that progressive multifocal leukoencephalopathy should be considered in any chronic lymphocytic leukemia patient with unexplained neurological sympto...

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Veröffentlicht in:International journal of general medicine 2009-01, Vol.2, p.5-7
Hauptverfasser: Ooi, Melissa G, Kelly, Peter J, Farrell, Michael, Murphy, Philip, O'Gorman, Peter
Format: Artikel
Sprache:eng
Schlagworte:
Agent Orange
Case Report
chronic lymphocytic leukemia
Encephalitis
fludarabine
intrathecal cytosine arabinoside
JC virus
Leukemia
progressive multifocal leukoencephalopathy
Viral infections
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container_title International journal of general medicine
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creator Ooi, Melissa G
Kelly, Peter J
Farrell, Michael
Murphy, Philip
O'Gorman, Peter
description We report a case of progressive multifocal leukoencephalopathy developing in a fludarabine-naïve patient with chronic lymphocytic leukemia. We suggest that progressive multifocal leukoencephalopathy should be considered in any chronic lymphocytic leukemia patient with unexplained neurological symptoms. Treatment history does not necessarily require fludarabine. Intrathecal cytosine arabinoside although unsuccessful in this patient, is a therapeutic option to consider in patients experiencing side effects from systemic therapy.
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subjects Agent Orange
Case Report
chronic lymphocytic leukemia
Encephalitis
fludarabine
intrathecal cytosine arabinoside
JC virus
Leukemia
progressive multifocal leukoencephalopathy
Viral infections
title Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia
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