Developmental selenomethionine and methylmercury exposures affect zebrafish learning

Abstract Methylmercury (MeHg) is a ubiquitous environmental pollutant and has been shown to affect learning in vertebrates following relatively low exposures. Zebrafish were used to model long-term learning deficits after developmental MeHg exposure. Selenomethionine (SeMet) co-exposure was used to...

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Veröffentlicht in:	Neurotoxicology and teratology 2010-03, Vol.32 (2), p.246-255
Hauptverfasser:	Smith, Leigh E, Carvan, Michael J, Dellinger, John A, Ghorai, Jugal K, White, Donald B, Williams, Frederick E, Weber, Daniel N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - drug effects Brain - growth & development Brain - physiopathology Cell Proliferation - drug effects Cytoprotection - drug effects Cytoprotection - physiology Danio rerio Developmental exposure Disease Models, Animal Dose-Response Relationship, Drug Emergency Female Learning Learning - drug effects Learning - physiology Learning Disorders - chemically induced Learning Disorders - drug therapy Learning Disorders - physiopathology Male Medical Education Mercury Methylmercury Compounds - antagonists & inhibitors Methylmercury Compounds - toxicity Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Neuropsychological Tests Neurotoxicity Syndromes - drug therapy Neurotoxicity Syndromes - physiopathology Neurotoxins - antagonists & inhibitors Neurotoxins - toxicity Selenium Selenomethionine - pharmacology Selenomethionine - therapeutic use Space Perception - drug effects Space Perception - physiology Spatial alternation Telencephalon - drug effects Telencephalon - growth & development Telencephalon - physiopathology Treatment Outcome Zebrafish
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