Overexpression of stathmin1 in the diffuse type of gastric cancer and its roles in proliferation and migration of gastric cancer cells

Background: Stathmin1 is a microtubule-regulating protein that has an important role in the assembly and disassembly of the mitotic spindle. The roles of stathmin1 in carcinogenesis of various cancers, including prostate and breast cancer, have been explored. However, its expression and roles in gas...

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Veröffentlicht in:	British journal of cancer 2010-02, Vol.102 (4), p.710-718
Hauptverfasser:	Jeon, T-Y, Han, M-E, Lee, Y-W, Lee, Y-S, Kim, G-H, Song, G-A, Hur, G-Y, Kim, J-Y, Kim, H-J, Yoon, S, Baek, S-Y, Kim, B-S, Kim, J-B, Oh, S-O
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/199 692/420/755 692/699/67/1504/1829 692/700/1750/1976 Aged Animals Biomedical and Life Sciences Biomedicine Cancer Research Carcinoma - genetics Carcinoma - metabolism Carcinoma - mortality Carcinoma - pathology Case-Control Studies Cell cycle Cell Movement - drug effects Cell Movement - genetics Cell Proliferation - drug effects Cells, Cultured Drug Resistance Epidemiology Female Gastric cancer Gene Expression Regulation, Neoplastic - drug effects Humans Kinases Lymphatic system Male Medical prognosis Medical research Metastasis Mice Mice, Nude Middle Aged Molecular Medicine Neoplasm Invasiveness Oncology Oral cancer Pathology Polyclonal antibodies Prostate cancer Proteins RNA, Small Interfering - pharmacology Stathmin - antagonists & inhibitors Stathmin - genetics Stathmin - metabolism Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - mortality Stomach Neoplasms - pathology Translational Therapeutics Tumors Up-Regulation - drug effects Xenograft Model Antitumor Assays
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