Neuroprotectin D1 attenuates laser-induced choroidal neovascularization in mouse

To examine the effects of neuroprotectin D1 (NPD1), a stereospecific derivative of docosahexaenoic acid, on choroidal neovascularization (CNV) in a laser-induced mouse model. Specifically, this was assessed by clinically grading laser-induced lesions, measuring leakage area, and volumetrically quant...

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Veröffentlicht in:	Molecular vision 2010-03, Vol.16, p.320-329
Hauptverfasser:	Sheets, Kristopher G, Zhou, Yongdong, Ertel, Monica K, Knott, Eric J, Regan, Jr, Cornelius E, Elison, Jasmine R, Gordon, William C, Gjorstrup, Per, Bazan, Nicolas G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Proliferation - drug effects Cell Size - drug effects Choroidal Neovascularization - chemically induced Choroidal Neovascularization - prevention & control Docosahexaenoic Acids - pharmacology Endothelial Cells - drug effects Endothelial Cells - pathology Fluorescein - metabolism Fluorescein Angiography Fundus Oculi Lasers Male Mice Mice, Inbred C57BL Microscopy, Confocal Retina - drug effects Retina - pathology
Online-Zugang:	Volltext
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