The Isolation and Characterization of Murine Macrophages
Macrophages are mononuclear phagocytes that are widely distributed throughout the body. These cells can contribute to development and homeostasis and participate in innate and adaptive immune responses. The physiology of macrophages can vary tremendously depending on the environment in which they re...
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| Veröffentlicht in: | Current Protocols in Immunology 2008-11, Vol.83 (1), p.14.1.1-14.1.14 |
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| container_end_page | 14.1.14 |
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| container_title | Current Protocols in Immunology |
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| creator | Zhang, Xia Goncalves, Ricardo Mosser, David M. |
| description | Macrophages are mononuclear phagocytes that are widely distributed throughout the body. These cells can contribute to development and homeostasis and participate in innate and adaptive immune responses. The physiology of macrophages can vary tremendously depending on the environment in which they reside and the local stimuli to which they are exposed. Macrophages are prodigious secretory cells, and in that role can promote and regulate immune responses and contribute to autoimmune pathologies. Macrophages are highly phagocytic, and in this capacity have long been considered to be essential immune effector cells. The important roles of macrophages in maintaining homeostasis and in contributing to tissue remodeling and wound healing is sometimes overlooked because of their vital role in host defense. Curr. Protoc. Immunol. 83:14.1.1‐14.1.14. © 2008 by John Wiley & Sons, Inc. |
| doi_str_mv | 10.1002/0471142735.im1401s83 |
| format | Article |
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These cells can contribute to development and homeostasis and participate in innate and adaptive immune responses. The physiology of macrophages can vary tremendously depending on the environment in which they reside and the local stimuli to which they are exposed. Macrophages are prodigious secretory cells, and in that role can promote and regulate immune responses and contribute to autoimmune pathologies. Macrophages are highly phagocytic, and in this capacity have long been considered to be essential immune effector cells. The important roles of macrophages in maintaining homeostasis and in contributing to tissue remodeling and wound healing is sometimes overlooked because of their vital role in host defense. Curr. Protoc. Immunol. 83:14.1.1‐14.1.14. © 2008 by John Wiley & Sons, Inc.</description><identifier>ISSN: 1934-3671</identifier><identifier>EISSN: 1934-368X</identifier><identifier>DOI: 10.1002/0471142735.im1401s83</identifier><identifier>PMID: 19016445</identifier><language>eng</language><publisher>United States</publisher><subject>Animals ; Antigens, CD - analysis ; Antigens, CD - immunology ; biomarkers ; Biomarkers - analysis ; bone marrow ; Bone Marrow - immunology ; Bone Marrow - metabolism ; colony stimulating factor ; flow cytometry ; lung ; Macrophages, Alveolar - immunology ; Macrophages, Alveolar - metabolism ; Macrophages, Peritoneal - immunology ; Macrophages, Peritoneal - metabolism ; Mice ; peritoneal cavity</subject><ispartof>Current Protocols in Immunology, 2008-11, Vol.83 (1), p.14.1.1-14.1.14</ispartof><rights>Copyright © 2008 John Wiley & Sons, Inc.</rights><rights>Copyright 2008 by John Wiley & Sons, Inc.</rights><rights>Copyright © 2008 John Wiley & Sons, Inc. 2008</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4381-c42ace60f5500c8f31d951ceeb9dd9c78efd3cf7075eaf957a7b745d3b6bdf0e3</citedby><cites>FETCH-LOGICAL-c4381-c42ace60f5500c8f31d951ceeb9dd9c78efd3cf7075eaf957a7b745d3b6bdf0e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19016445$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Xia</creatorcontrib><creatorcontrib>Goncalves, Ricardo</creatorcontrib><creatorcontrib>Mosser, David M.</creatorcontrib><title>The Isolation and Characterization of Murine Macrophages</title><title>Current Protocols in Immunology</title><addtitle>Curr Protoc Immunol</addtitle><description>Macrophages are mononuclear phagocytes that are widely distributed throughout the body. 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Immunol. 83:14.1.1‐14.1.14. © 2008 by John Wiley & Sons, Inc.</description><subject>Animals</subject><subject>Antigens, CD - analysis</subject><subject>Antigens, CD - immunology</subject><subject>biomarkers</subject><subject>Biomarkers - analysis</subject><subject>bone marrow</subject><subject>Bone Marrow - immunology</subject><subject>Bone Marrow - metabolism</subject><subject>colony stimulating factor</subject><subject>flow cytometry</subject><subject>lung</subject><subject>Macrophages, Alveolar - immunology</subject><subject>Macrophages, Alveolar - metabolism</subject><subject>Macrophages, Peritoneal - immunology</subject><subject>Macrophages, Peritoneal - metabolism</subject><subject>Mice</subject><subject>peritoneal cavity</subject><issn>1934-3671</issn><issn>1934-368X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNUNtKw0AQXUSxpfYPRPIDrTvZ3WzigyDBS6FFHyr4tmz20iykSdltlfr1pqSk-ubLzGHmnDPDQega8BQwjm8x5QA05oRN3RoohpCSMzSEjNAJSdKP8x5zGKBxCK7AGGJCKU8u0QAyDAmlbIjSZWmiWWgquXVNHclaR3kpvVRb4913N2xstNh5V5toIZVvNqVcmXCFLqysghkf-wi9Pz0u85fJ_PV5lj_MJ4qSFNoaS2USbBnDWKWWgM4YKGOKTOtM8dRYTZTlmDMjbca45AWnTJMiKbTFhozQfee72RVro5Wpt15WYuPdWvq9aKQTfze1K8Wq-RRxSihjtDWgnUH7egje2F4LWBzCFKcwRR9mK7v5ffckOkbXEu46wperzP5fpiJ_my0OmPwABN6DiQ</recordid><startdate>200811</startdate><enddate>200811</enddate><creator>Zhang, Xia</creator><creator>Goncalves, Ricardo</creator><creator>Mosser, David M.</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>200811</creationdate><title>The Isolation and Characterization of Murine Macrophages</title><author>Zhang, Xia ; Goncalves, Ricardo ; Mosser, David M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4381-c42ace60f5500c8f31d951ceeb9dd9c78efd3cf7075eaf957a7b745d3b6bdf0e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Animals</topic><topic>Antigens, CD - analysis</topic><topic>Antigens, CD - immunology</topic><topic>biomarkers</topic><topic>Biomarkers - analysis</topic><topic>bone marrow</topic><topic>Bone Marrow - immunology</topic><topic>Bone Marrow - metabolism</topic><topic>colony stimulating factor</topic><topic>flow cytometry</topic><topic>lung</topic><topic>Macrophages, Alveolar - immunology</topic><topic>Macrophages, Alveolar - metabolism</topic><topic>Macrophages, Peritoneal - immunology</topic><topic>Macrophages, Peritoneal - metabolism</topic><topic>Mice</topic><topic>peritoneal cavity</topic><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Xia</creatorcontrib><creatorcontrib>Goncalves, Ricardo</creatorcontrib><creatorcontrib>Mosser, David M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Current Protocols in Immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Xia</au><au>Goncalves, Ricardo</au><au>Mosser, David M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Isolation and Characterization of Murine Macrophages</atitle><jtitle>Current Protocols in Immunology</jtitle><addtitle>Curr Protoc Immunol</addtitle><date>2008-11</date><risdate>2008</risdate><volume>83</volume><issue>1</issue><spage>14.1.1</spage><epage>14.1.14</epage><pages>14.1.1-14.1.14</pages><issn>1934-3671</issn><eissn>1934-368X</eissn><abstract>Macrophages are mononuclear phagocytes that are widely distributed throughout the body. 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| fulltext | fulltext |
| identifier | ISSN: 1934-3671 |
| ispartof | Current Protocols in Immunology, 2008-11, Vol.83 (1), p.14.1.1-14.1.14 |
| issn | 1934-3671 1934-368X |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Antigens, CD - analysis Antigens, CD - immunology biomarkers Biomarkers - analysis bone marrow Bone Marrow - immunology Bone Marrow - metabolism colony stimulating factor flow cytometry lung Macrophages, Alveolar - immunology Macrophages, Alveolar - metabolism Macrophages, Peritoneal - immunology Macrophages, Peritoneal - metabolism Mice peritoneal cavity |
| title | The Isolation and Characterization of Murine Macrophages |
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