The Ubiquitin-Like Protein FAT10 Mediates NF-κB Activation

NF-κB is a central mediator of innate immunity and contributes to the pathogenesis of several renal diseases. FAT10 is a TNF-α–inducible ubiquitin-like protein with a putative role in immune response, but whether FAT10 participates in TNF-α–induced NF-κB activation is unknown. Here, using renal tubu...

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Veröffentlicht in:Journal of the American Society of Nephrology 2010-02, Vol.21 (2), p.316-326
Hauptverfasser: PENGFEI GONG, CANAAN, Allon, ROSS, Michael J, BIN WANG, LEVENTHAL, Jeremy, SNYDER, Alexandra, NAIR, Viji, COHEN, Clemens D, KRETZLER, Matthias, D'AGATI, Vivette, WEISSMAN, Sherman
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Sprache:eng
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