Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD

Common variants in the region of the UMOD gene, which encodes uromodulin (Tamm-Horsfall protein), associate with chronic kidney disease (CKD) and estimated GFR (eGFR). Whether uromodulin levels associate with UMOD variants or with the risk for developing CKD is unknown. We conducted an age- and gend...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Society of Nephrology 2010-02, Vol.21 (2), p.337-344
Hauptverfasser:	KÖTTGEN, Anna, HWANG, Shih-Jen, GUDNASON, Vilmundur, SHLIPAK, Michael G, QIONG YANG, CORESH, Josef, LEVY, Daniel, FOX, Caroline S, LARSON, Martin G, VAN EYK, Jennifer E, QIN FU, BENJAMIN, Emelia J, DEHGHAN, Abbas, GLAZER, Nicole L, LINDA KAO, W. H, HARRIS, Tamara B
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences Case-Control Studies Chronic Disease Clinical Epidemiology Female Genetic Predisposition to Disease - genetics Genotype Glomerular Filtration Rate - physiology Humans Kidney Diseases - genetics Kidney Diseases - physiopathology Kidney Diseases - urine Kidney Diseases, Cystic - genetics Kidneys Male Medical sciences Middle Aged Molecular Motor Proteins - genetics Mucoproteins - genetics Mucoproteins - urine Myosin Heavy Chains - genetics Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Polymorphism, Single Nucleotide - genetics Renal failure Risk Factors Urinary system involvement in other diseases. Miscellaneous Uromodulin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!