Downregulation of Epidermal Growth Factor Receptor Expression Contributes to α-TEA's Proapoptotic Effects in Human Ovarian Cancer Cell Lines

RRR-α-tocopherol derivative α-TEA (RRR-α-tocopherol ether-linked acetic acid analog) has been shown to be a potent antitumor agent both in vivo and in vitro. In this study, we investigated the effects of α-TEA on the expression of epidermal growth factor receptor (EGFR) family members, ErbB1, 2 and...

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Veröffentlicht in:Journal of oncology 2010-01, Vol.2010 (2010), p.1-11
Hauptverfasser: Shun, Ming-Chieh, Yu, Weiping, Park, Sook-Kyung, Sanders, Bob G., Kline, Kimberly
Format: Artikel
Sprache:eng
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